The Total Barrier Stack (BPC-157 + KPV) 120 Capsules
99.0+ % Purity Guaranteed | NF-kB Signal Suppression & Tight-Junction Homeostasis Research
The Total Barrier Stack
BPC-157 (0.5mg) + KPV (250mcg) | 120 Capsules
Targeted Research Project: NF-kB Signal Suppression & Tight-Junction Homeostasis Research
The Total Barrier Stack is a dual-action research protocol engineered to study the maintenance and repair of mucosal and epithelial membranes. This project investigates the synergy between the gastric-derived pentadecapeptide BPC-157 and the tripeptide KPV, focusing on the restoration of tight-junction stability during active inflammatory signaling.
Primary Research Focus
- Structural Reconstruction (BPC-157): BPC-157 (Body Protection Compound) is extensively researched for its role in promoting angiogenesis and the upregulation of growth hormone receptors in connective and epithelial tissues. In research models, it is utilized to study the physical “healing” of the gut lining and skin barrier.
- Pathway Silencing (KPV): KPV is a potent C-terminal tripeptide fragment of $\alpha$-MSH. Its primary research utility lies in its ability to enter the cell nucleus and directly inhibit the NF-kB signaling pathway—the master regulator of inflammatory cytokine production.
- Homeostatic Synergy: This protocol models a “Seal and Silence” mechanism. Researchers observe if the chemical silencing of inflammatory “noise” by KPV creates the optimal environment for BPC-157 to execute the physical reconstruction of the tissue barrier.
- Stability: KPV is a highly robust molecule and does not require refrigeration. BPC-157 in this micro-filled capsule format is shelf-stable for transport and standard laboratory storage.
LABORATORY RESEARCH USE ONLY. This product is a chemical substance, not a drug, food, or supplement. Not approved by the FDA or EMA. Strictly not for human or animal consumption.
Technical Specifications
| Specification | Data Details |
|---|---|
| Purity | 99.0+ % Purity Guaranteed |
| Catalog # | RUO STACKS |
| Sequence | BPC-157: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val / KPV: Lys-Pro-Val |
| Molecular Formula | BPC-157: C62H98N16O22 / KPV: $C_{16}H_{30}N_{4}O_{4}$ |
| Storage | Room temperature 20 C- 25 C - long-term storage at 2-8 C is recommended. |
Why PepGen Lab?
Lab-Grade Purity
Every batch comes with a third-party Certificate of Analysis verifying HPLC purity and mass spectrometry identity to guarantee research reliability.
Extreme Stability
Optimized arginine bond configuration enables ambient temperature transit shipping from our hubs without loss of structural integrity.
Direct-to-Lab Value
Skip local middleman markups. We ship direct from specialized biotech synthesizers to deliver premium research compounds cost-efficiently.